CEPID 2013-2024 


Principal Investigator:
Fernando de Queiroz Cunha

Education and Knowledge Diffusion Coordinator: 
Rita de Cassia Aleixo Tostes Passaglia
Technology Transfer Coordinator: João Santana da Silva

University of São Paulo (USP) 
Av. Bandeirantes, 3900
14049-900 - Ribeirão Preto, SP - Brasil
55 16 3315-3324

Center leaflet (pdf):

Center for Research on Inflammatory Diseases

Study helps understand how defense cells combat bacteria

Researchers find that different types of inflammasomes – protein complexes responsible for initiating an inflammatory response in macrophages – can regulate each other to amplify signals of infection

Study explains why patients with shingles feel pain

Article published in The Journal of Neuroscience shows role of cytokine TNF in genesis of herpetic neuralgia. Discovery could lead to novel therapeutic approaches

Study reveals mechanism that leads to immunosuppression after sepsis

In an article published in Nature Communications, researchers describe a cascade of events that unbalances the immune system, increasing the risk of recurring infections and death

Researchers describe novel strategy for combating sepsis

Studies in mice suggest that two drugs capable of inhibiting the enzyme TrxR-1 – available commercially for other purposes – reduce inflammation and mortality in patients with sepsis

Key substance for treatment of visceral leishmaniasis identified

Paper published in Infection and Immunity shows that stimulating production of cytokine IL-17A in infected organism helps reduce parasite load and prevents lesions in organs

Initial findings of BIPMed were presented during FAPESP Week

Data from a study involving carriers of dystonia presented in Michigan demonstrate the importance of gathering genetic data on reference populations in Brazil

Study deepens understanding of molecular genetics in diabetes mellitus

Researchers find that microRNAs undermine the control of gene expression in T-lymphocytes, leading these defense cells to attack insulin-producing beta cells in the pancreas

Launch of Latin America's first public human genome database

The platform was developed as part of BIPMed, the Brazilian Initiative on Precision Medicine, an effort promoted by members of five research centers supported by FAPESP