SITE: http://redoxoma.iq.usp.br

Principal Investigator:
Ohara Augusto 
 
Education and Knowledge Diffusion Coordinator: Carmen Fernandez 
 
Technology Transfer Coordinator: Paolo Di Mascio

HOST INSTITUTION
University of São Paulo (USP)
Av. Prof. Lineu Prestes, 748
Cidade Universitária
05508-000 - São Paulo, SP - Brasil

ASSOCIATED INSTITUTIONS
Aarhus University, Denmark
AC Camargo Cancer Center
Atomic Energy and Alternative Energies Commission (CEA), France
Boston University, USA
Butantan Institute (IBu)
Centre National de la Recherche Scientifique (CNRS), France
Emory University, USA
Federal University of São Paulo (UNIFESP)
Harvard University, USA
Heart Institute (INCOR/USP)
Koç University, Turkey
Liverpool John Moores University, United Kingdom
National Institute on Aging (NIA), USA
São Paulo State University (UNESP)
University of Madrid, Spain
University of Milwaukee, USA
University of Rochester, USA

Center leaflet (pdf):

Center for Research on Redox Processes in Biomedicine

Study helps understand functioning of anti-oxidant enzyme

Scientists at the Center for Research on Redox Processes in Biomedicine (Redoxome) show that an enzyme capable of ridding cells of an oxidizing substance can be found in different parts of the mitochondrion

Colored sunscreen protects skin from damage caused by visible light

Study performed at the Center for Research on Redox Processes in Biomedicine elucidates action mechanism of visible light on skin and questions typical use of sunscreen

Less fat, more hair, young skin

A study shows that caloric restriction diet reduces body fat and increases fur production in mice. This research from the University of São Paulo, in Brazil, was published in Cell Reports

Researchers investigate how caloric restriction benefits cellular functioning

Experiments with animals show dietary intervention makes mitochondria work better

Novel mechanism of uric acid's inflammatory action described

Inflammation caused by uric acid does not depend on high plasma levels of the substance or a mechanical lesion due to uric acid crystals, according to scientists at the Center for Research on Redox Processes in Biomedicine

Researchers produce artificial compounds with anti-tumor activity

Complexes that associate essential metals with organic ligands could be used in cancer drugs

Researchers describe novel strategy for combating sepsis

Studies in mice suggest that two drugs capable of inhibiting the enzyme TrxR-1 – available commercially for other purposes – reduce inflammation and mortality in patients with sepsis

Enzyme helps bacteria defend themselves against oxidants secreted by immune system

Article published in PNAS describes how researchers identified biological substrates of bacterial enzyme Ohr, a potential target for drug development