Research at the cutting edge of knowledge

The São Paulo Research Foundation (FAPESP) supports Research, Innovation and Dissemination Centers (RIDCs) selected for funding for a period of up to eleven years. Each RIDC is expected to establish hub of excellent research in focus area, and must actively seek out and develop opportunities to have its research results contribute to high-impact applications, as well as contributing to education and dissemination of knowledge.

Post-Doctoral Fellowship in Computational Fluid Dynamics / Hybrid Particle-Mesh Methods

The positions aims at developing and implementing a particle-mesh model (SPH-FEM or MPS-FEM) coupled by boundary integrals, in order to accelerate large scale numerical simulations of fluid-structure interactions involving free-surface flows and deformable structures.

Post-Doctoral Fellowship in Computational Fluid Dynamics / Multiscale Domain Decomposition Methods

The objective is the development of multiscale domain decomposition methods and its implementation in a high-performance computing environment, for the direct numerical simulation of incompressible flows.

Post-Doctoral Fellowship in Image Processing and Machine Learning

This position focuses on detecting and forecasting floods using images and thus automating flood identification without human intervention.

Post-Doctoral Fellowship in Obesity Research

Project aims at identifying new biomarkers for metabolic diseases based on cutting-edge technology, such as single-cell RNA sequencing.

Post-Doctoral Fellowship in Risk Factors for COVID-19

This project aims to unravel the risk factors and mechanisms underlying the greater susceptibility of elderly and obese individuals to progression to the severe stage of COVID-19.

Post-Doctoral Fellowship in Modelling the Wheatley Heart Valve

The project involves the mathematical modeling of blood flow through an artificial heart valve which consists of a titanium ring attached to a special flexible polymer.

Study reveals arsenal used by parasite to inhibit cellular defense and aggravate leishmaniasis

Group affiliated with the Center for Research on Inflammatory Diseases showed that the parasite blocks the action of an enzyme using autophagy.

Post-Doctoral Fellowship in Cellular Biology / Pharmacology

The project aims to identify peptides derived from animal venoms with antitumor and immunomodulatory potential, evaluated in models of cutaneous melanoma and experimental autoimmune encephalomyelitis.

Cell-mediated immunity is essential to prevent reinfection by the novel coronavirus

HUG-CELL researchers studied the case of identical twins in which only one sibling was reinfected and developed complications after a second exposure to the virus. Their analysis showed that the adaptive immune response can be different even between individuals with the same genome.

Study maps immune system genes involved in resistance to SARS-CoV-2

A study at HUG-CELL analyzed genetic material from 86 couples in which only one spouse was infected. The results suggest that more frequent variants in the resistant spouses could lead to more efficient activation of natural killer (NK) cells, which are part of the innate immune system.

Atlas of human lung helps understand effects of novel coronavirus on alveoli

RIDC OCRC researchers reveal the mechanisms whereby SARS-CoV-2 disrupts the regulation of inflammation, coagulation and blood pressure when it infects alveolar cells, responsible for gas exchange in the lungs.

Novel water decontamination method combines low-cost composites and solar energy

A simple and affordable solution developed by researchers at CeRTEV and a Nigerian collaborator eliminates even multi-resistant bacteria. Clay, papaya seeds and banana peel are among the raw materials used by the group.

Molecule with potential to treat multiple sclerosis and asthma passes toxicology testing in zebrafish

Study conducted at CeTICS shows that anti-inflammatory peptide TnP could lead to drug development.

Study shows how low-protein intake during pregnancy can cause renal problems in offspring

In an article published in PLOS ONE, scientists at RIDC OCRC describe the impact of hypoproteinemia on the expression of microRNAs associated with kidney development in rat embryos.

Post-Doctoral Fellowship in Design of FPGA Hardware Acceleration

Project at the Center for Computing in Engineering and Sciences focus on solutions for Science- and Engineering-related problems using a fiber-optics interconnected FPGA cluster that works as a fast Multi-FPGA architecture.