BV-FAPESP: research projects supported in this Center
CRID in the Media: news about the Center
The Center for Research in Inflammatory Diseases (CRID) was created with the aim of producing integrative and translational scientific research to identify and validate new biological pathways involved in the induction and resolution of inflammation. To this end, it counts on the experience of researchers from various fields of Biomedical Sciences linked to basic research (genetics, molecular and cell biology, immunology, pharmacology, and pathology) and clinical research (rheumatology, immunology, infectology, and dermatology), in addition to researchers in the area of bioinformatics.
Inflammatory diseases constitute a complex and heterogeneous group of diseases that affect more than 10% of the world population. The treatment alternatives currently available are limited and, in some cases, ineffective, considering that information on the underlying mechanisms of the inflammatory process and the pathophysiology of inflammatory diseases is still lacking.
The specific objective of the Center is to advance knowledge about inflammatory diseases (infectious, autoimmune, and related to the cardiovascular system) to recognize and understand the molecular, immunological, pathological, and pharmacological mechanisms involved; identify new biological targets for the development of pharmacological therapeutic tools; search for possible diagnostic markers and prognostic indications, and apply new knowledge to design and synthesize molecules aimed at treating inflammatory diseases.
2020-04-15
Metabolic changes associated with diseases such as pulmonary hypertension and chronic obstructive pulmonary disease may reprogram gene expression to increase production of a protein used by SARS-CoV-2 to penetrate lung cells.
2020-01-23
Partnering with scientists at Harvard, a group of Brazilians affiliated with the Center for Research on Inflammatory Diseases (CRID), supported by FAPESP, described the mechanisms that cause hair color loss in extreme situations.
2019-12-04
A Brazilian team at FAPESP-supported Center for Research on Inflammatory Diseases identified the strategy used by immune cells to combat the pathogen Mayaro virus, which causes symptoms similar to those of chikungunya fever. These results pave the way for the development of drugs.
2019-10-02
Phylogenomic analysis shows that pathogen isolated in Brazilian hospital does not belong to the genus Leishmania. Researchers are investigating whether this species alone can cause severe disease or intensifies symptoms in co-infected patients.
2019-07-03
Scientists at the Center for Research on Inflammatory Diseases (CRID) show why pediatric patients with sepsis suffer from more inflammation and organ injury than adults. New treatment strategies may be tested.
2019-06-05
Graduate students and researchers from any country have until June 23 to apply for this event, which is supported by FAPESP and will take place at the University of São Paulo’s Ribeirão Preto Medical School in Brazil.
