A method created in Brazil by the Human Genome and Stem Cell Research Center could be used for large-scale production of livers for transplantation.
Analysis of DNA from 1,171 over-sixties living in São Paulo will enable scientists to identify genetic mutations responsible for diseases or important to healthy aging, according to the authors, which are linked to HUG-CELL.
The dysregulation appeared to affect communication among neurons in the subjects of a study conducted at HUG-CELL. The discovery could improve diagnosis, which is currently based on the clinical analysis of symptoms.
Designed by the Human Genome and Stem Cell Research Center, the novel test may cost a quarter of those based on RT-PCR, considered the gold standard for diagnosis of the disease.
Findings reported by HUG-CELL researchers in PLOS Neglected Tropical Diseases help explain why only some babies whose mothers are infected during pregnancy are born with microcephaly and other anomalies.
A study is being conducted at HUG-CELL to determine whether people who develop severe forms of the disease have risk genes and whether asymptomatic people or patients with only mild symptoms have protective genes.
The viral therapy was tested in three elderly animals with spontaneous brain tumors by a group affiliated with the Human Genome and Stem Cell Research Center.
Technique developed at Human Genome and Stem Cell Research Center, hosted by the University of São Paulo, produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future.