WEBSITE: www.ocrc.org.br
 
Principal Investigator: Licio Augusto Velloso 
 
Education and Knowledge Diffusion Coordinator: Ronaldo Aloise Pilli 
 
Technology Transfer Coordinator: João Eduardo de Morais Pinto Furtado

HOST INSTITUTION
University of Campinas (UNICAMP)
Rua Carl Von Linnaeus, s/n, Bloco Z - IB/Unicamp
Cidade Universitária Zeferino Vaz - Barão Geraldo
13083-864 - Campinas, SP 
55 19 3521-2695 

ASSOCIATED INSTITUTIONS
University of São Paulo (USP)
São Paulo State University (UNESP) 
Federal University of São Paulo (UNIFESP)

Center leaflet (pdf):

Obesity and Comorbidities Research Center

Atlas of human lung helps understand effects of novel coronavirus on alveoli

RIDC OCRC researchers reveal the mechanisms whereby SARS-CoV-2 disrupts the regulation of inflammation, coagulation and blood pressure when it infects alveolar cells, responsible for gas exchange in the lungs.

Study shows how low-protein intake during pregnancy can cause renal problems in offspring

In an article published in PLOS ONE, scientists at RIDC OCRC describe the impact of hypoproteinemia on the expression of microRNAs associated with kidney development in rat embryos.

Researchers at RIDC OCRC discover mechanism that makes COVID-19 more severe in diabetics

Higher blood glucose levels captured by defense cells provide energy for augmented viral replication, triggering overwhelming immune response that kills lung cells.

Researchers will study body fat immune cells to understand obesity-associated inflammation

Scientists associated with the RIDC OCRC are the only Latin American group to have had a project selected in an international request for applications by the CZI. More than USD 175,000 has been awarded to the study, which will be the first in Brazil to use single-cell analysis.

FAPESP selects first projects in call to combat COVID-19

Amongst all proposals the Scientific Board analyzed by March 31, two were selected, including a study at OCRC that evaluates the effectiveness of drugs that inhibit bradykinin against pulmonary inflammation in critical patients.

Novel blood test points to risk of weight gain and diabetes

The blood test method makes use of machine learning and can be used to predict whether patients will put on weight, unless they change their habits. The project was conducted under the aegis of the Obesity and Comorbidities Research Center.

Zika inhibits the proliferation of prostate cancer cells

Experiments conducted under the aegis of the Obesity and Comorbidities Research Center showed that Zika virus inhibits tumor cell proliferation even when inactivated by high temperature.

Study allows establishing a timeline of obesity

In experiments with mice, research group showed that a diet rich in saturated fats damages the system of the brain that controls hunger well before it alters the profile of intestinal bacteria