Brazilian researchers discover key gene regulating virulence of fungus that causes severe lung infections

The researchers are now looking for a molecule that inactivates the protein expressed by the gene as a basis for a drug that could complement existing medications, which are not always effective and can have adverse side-effects.

Study details efficacy of alternatives to use of mammals in experiments

Among the advantages of the novel methodologies is the possibility of using human cells, leading to higher success rates in the transition from preclinical to clinical trials.

In a book, a scientist narrates a journey through the Anthropocene, with an optimistic ending

Center for Research on Biodiversity Dynamics and Climate Change

A member of the Center for Research on Biodiversity Dynamics and Climate Change, Mauro Galetti uses his experience from his undergraduate studies in biology to his most recent studies in ecology to tell stories in accessible language that inspire readers to fight for the planet.

Tool checks for common articles and projects between candidate and reviewer CVs

Center for Research on Inflammatory Diseases

Developed by a laboratory associated with the Center for Research in Inflammatory Diseases, “Conflitulus Lattes” – named after the Brazilian system of information on science and technology – helps avoid conflicts of interest in review panels.

Preterm delivery by cesarean section is a growing tendency in Brazil and entails risks for babies, study shows

Brazilian researchers investigated the effects of delivery date manipulation to avoid the Carnival holiday. Their findings suggest Brazilian women are giving birth too early, impairing the health of their babies.

Research group identifies novel probiotics in traditional Brazilian cheeses

In the journal Current Microbiology, Brazilian researchers describe how three strains of bacteria in the genus Lactobacillus can benefit human health and meet the needs of the cheese industry.

Directors of FAPESP meet with new United States Consul General in São Paulo

Richard Glenn’s aim on his first official visit to Brazil was to strengthen the ties of partnership with FAPESP.

Sustainable agricultural systems reduce greenhouse gas emissions

Center for Carbon Research in Tropical Agriculture

Scientists at the University of São Paulo present this conclusion based on a systematic review of the literature in a paper published in the Journal of Cleaner Production.

FAPESP launches four Science for Development Centers that will work to promote inclusion

Partnerships among departments of the São Paulo State Government, universities and research centers aim to meet society’s needs by developing devices, software and processes that promote assistance, rehabilitation, and better lives for people with disabilities.

Automated coffee sorting helps select beans for export

A system created by a startup supported by FAPESP evaluates coffee cherry quality with precision on the production line, reducing waste and enhancing yield.

Book covers the complete sequence of a data science project

Center for Research in Mathematical Sciences Applied to Industry

The publication by André de Carvalho, a researcher at the Center for Mathematical Sciences Applied to Industry, is suitable for undergraduates, postgraduates, and professionals.

Researchers map brain circuits that signal immediate danger and create memories to help avoid threats

Experiments with mice at the University of São Paulo used cutting-edge techniques to investigate the neural circuits behind aversive behavior and fear memory. The findings are reported in Current Biology.

To subvert immune response, COVID virus stimulates production of proteins without protective function

According to Brazilian researchers, SARS-CoV-2 uses this strategy to manipulate the machinery of the host’s defense cells. The discovery paves the way for the development of novel therapies.

A book on challenges to an inclusive bioeconomy in the Amazon

Thirty-two experts affiliated with academic and research institutions in the North, Northeast and Southeast regions of Brazil wrote its 12 chapters.

Study details effects of laser and electron irradiation of silver-based compounds

Center for Research and Development of Functional Materials

An article reporting the study is featured on the cover of Nano Letters; the findings can help design next-generation electronic materials for the semiconductor and nanotechnology industry.

Brain enlargement is linked to severe symptoms of autism spectrum disorder, study shows

The researchers based their findings, published in Molecular Autism, on data for more than 900 children with ASD and experiments with brain organoids derived from blood cells donated by some of the children.

Molecules extracted from microalgae accelerate seed germination

A startup supported by FAPESP has created a solution that promotes development and growth of the roots and aerial part of plants.

Project in Brazil studies technologies to integrate offshore wind farms into the country's power grid

Work conducted at the Research Center for Greenhouse Gas Innovation will also analyze the best way to bring electricity to oil platforms off the Brazilian coast.

Study finds that dopaminergic medication improves sleep quality in Parkinson’s disease patients

The analysis was conducted by researchers at São Paulo State University (UNESP), showing that when the patients took the drug, the number of times they woke up during the night fell by 25% and the amount of time they remained awake fell 30% on average.

Oropouche virus: 200-fold increase in infections this year in Brazil compared to the last decade due to novel variant

Brazilian researchers publish preliminary data showing that the pathogen has undergone mutations making it more aggressive and contributing to resurgence of the disease in Brazil since 2023.

Platform uses artificial intelligence to calculate body measurements from photographs

The solution, developed by a startup supported by FAPESP, estimates eight parameters with an error of under 5% for 80% of users, according to the firm’s founder.

Resistance to the main drugs used in Brazil against Leishmania is found in parasite infecting cutaneous leishmaniasis patient

Trials conducted at the State University of Campinas (UNICAMP) confirm that the isolate of Leishmania amazonensis from a 46-year-old patient is resistant to amphotericin B.

Novel methodology for remote testing of functional mobility and muscle strength in elderly patients with dementia

The protocol was designed at the Federal University of São Carlos (UFSCar). Trained carers help patients take standard tests used by geriatricians and physical therapists, performing them in their own homes with remote assistance from health workers. The goal is to facilitate access to treatment for older people with dementia.

Chip that entangles four photons opens up possibility of inviolable quantum encryption

The device can be used to implement sharing systems in which any attempt at unauthorized access is immediately detected because it alters the quantum correlations.

Tool lists most effective strategies for increasing climate awareness and action

The international study involved more than 59,000 participants from 63 countries, including Brazil. By analyzing interventions that most influence people’s behavior, the work resulted in the creation of a tool that can be used by policymakers and environmental advocacy groups.