Obesity and Comorbidities Research Center
Infection by SARS-CoV-2 can suppress the expression of mitochondrial genes involved in production of ATP cell fuel in many vital organs. The discovery paves the way to a search for strategies to restore mitochondrial function.
Center for Research and Development of Functional Materials
The device, which combines magnetic fluorescent nanoparticles, was designed at the Center for Development of Functional Materials, a research center supported by FAPESP and hosted by the Federal University of São Carlos.
Center for Carbon Research in Tropical Agriculture
The Center for Carbon Research in Tropical Agriculture (CCARBON) is a Research, Innovation and Dissemination Center (RIDC) supported by FAPESP and hosted by the University of São Paulo’s Luiz de Queiroz College of Agriculture (ESALQ-USP). It was officially launched on November 17 and aims to make food, fiber and energy productivity part of the solution to the climate crisis.
Center for Research and Development of Functional Materials
A computational study conducted by the Center for Development of Functional Materials at the Federal University of São Carlos (UFSCar) in Brazil could help extend the working lives of these batteries, which are widely used by utilities and manufacturers.
Center for Research on Redox Processes in Biomedicine
Scientists at the University of São Paulo’s Center for Research on Redox Processes in Biomedicine used a novel technique they themselves developed to identify altered molecules in an animal model of amyotrophic lateral sclerosis (ALS).
Center for Research on Inflammatory Diseases
An article published in PNAS by Brazilian and Australian researchers describes a hitherto unknown protein with anti-oxidizing properties secreted by Coxiella burnetii, a Gram-negative intracellular bacterium, pointing to possible treatments for auto-immune diseases and even cancer.
Center for Research and Innovation in Biodiversity and Drug Discovery
Findings reported in the journal Antibiotics by scientists working in Brazil and the United States pave the way for the development of drugs against resistant bacteria.
Center for Cell-Based Therapy
Opened in 2022 with FAPESP’s support, Nutera is Latin America’s first cellular product manufacturing plant. It is run by researchers from Butantan Institute and the University of São Paulo’s Ribeirão Preto Blood Center, and could become a supplier to the SUS, Brazil’s public healthcare network.
Center for Carbon Research in Tropical Agriculture
Researchers at the University of São Paulo highlight the importance of monitoring these areas and advocate the use of technosols based on tailings and other waste to offset part of their emissions.
Center for Research, Teaching, and Innovation in Glass
Applications of specialty glass range from astronomy to medicine, as well as data and power transmission. The study combined spectroscopy and computational modeling to show how the structure of the material is affected by addition of niobium oxide.
Obesity and Comorbidities Research Center
In experiments with mice, researchers at the State University of Campinas observed alterations in feed consumption, weight gain, anxious behavior and an increase in central nervous system, adipose tissue and liver inflammation.
Optics and Photonics Research Center
Photodynamic therapy developed by the Center for Research in Optics and Photonics, which is supported by FAPESP, has been recommended by Brazil’s federal body responsible for including novel healthcare technologies in the national health service.
Center for Research and Development of Functional Materials
One of the goals of the study conducted by scientists at the Center for Development of Functional Materials and the Center for Innovation on New Energies is to reduce atmospheric emissions of this greenhouse gas.
Center for Research and Innovation in Biodiversity and Drug Discovery
Similar programs and FAPESP’s pragmatism arouse interest in intensifying collaboration and joint calls for proposals involving research centers in Switzerland and São Paulo.
Center for Research on Inflammatory Diseases
A team affiliated with a FAPESP-supported research center showed in mice that molecules capable of preventing the peptide C5a from binding to its cellular receptor helped prevent lung damage and other complications typical of severe COVID-19.
Center for Research on Inflammatory Diseases
A study conducted at the University of São Paulo and reported in PNAS explains hyperglycemia in hospitalized patients and shows how SARS-CoV-2 causes symptoms similar to those of diabetes.
Center for Research on Redox Processes in Biomedicine
Researchers at the University of São Paulo observed the effects of adiponectin in trials involving blood samples from lean and obese subjects. The discovery points to novel routes to treatment for type 2 diabetes and related dysfunctions.
Antimicrobial Resistance Institute of São Paulo (Aries Project)
A study conducted at the Federal University of São Paulo shows that 20% of patients with bloodstream infections are not treated, and at least half of those treated die. Diagnostic techniques must improve, the authors warn.
Brazilian Research Institute for Neuroscience and Neurotechnology
Brazilian researchers analyzed data from MRI scans and various tests to detect biological alterations linked to the neurological symptoms most reported by patients, especially anxiety, depression, sleepiness and fatigue. The latest results were presented to the ninth edition of BRAINN Congress.
Center for Research, Teaching, and Innovation in Glass
The technique was developed at the Federal University of São Carlos (UFSCar) in São Paulo state, Brazil, and could impact the manufacturing of batteries, smartphone screens and other devices.
Center for Research on Toxins, Immune-Response and Cell Signaling
A research group at Butantan Institute performed tests on animal models with asthma as a reference and demonstrated that the peptide from Thalassophryne nattereri, common in North and Northeast Brazil, is safe and efficacious.
